Systemic Lupus Erythematosus Mortality Rate

Mortality and causes of death during the study during the 10 year period 68 6 8 patients died 10 in the first year 11 in the second 8 in the third 7 in the fourth 9 in the fifth 7 in the sixth 4 in the seventh 4 in the eighth 7 in the ninth and 3 in the tenth. Our sample was a multisite international sle cohort 23 centers 9 547 patients. Approximately one third of deaths from sle occur among persons aged 45 years.

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Systemic lupus erythematosus mortality rate. Causes predictors and interventions. Sle is an autoimmune disease in which the immune system attacks its own tissues causing widespread inflammation and tissue damage in the affected organs. Deaths were ascertained by vital statistics registry linkage. Grupo de investigación en reumatología autoinmunidad y medicina traslacional fundación valle del lili and univesidad icesi cali colombia.

But the most serious problem congenital heart block requires a pacemaker and has a mortality rate of about 20. Survival curves differ significantly between sexes p 0 05 with a better prognosis for women. Mortality in systemic lupus erythematosus. To examine mortality rates in the larg est systemic lupus erythematosus sle cohort ever assembled.

Currently the average 10 year survival rate exceeds 90 67 63 and the 15 year survival rate is approximately 80. Data collected from the us centers for disease control and prevention cdc national vital statistics system have revealed that mortality from systemic lupus erythematous sle has decreased in all subpopulations including women and blacks over the past decade after periods of increasing rates reported between the 1970s and the 1990s according to the results of a population based study. Systemic lupus erythematosus or sle is an autoimmune disease that mistakenly attacks healthy tissue in the body and research shows it raises mortality rates by as much as 67 percent with young. To examine mortality rates in the largest systemic lupus erythematosus sle cohort ever assembled.

Deaths were ascertained by vital statistics registry linkage. Prior to 1955 the 5 year survival rate in sle was less than 50. Our sample was a multisite interna tional sle cohort 23 centers 9 547 patients. Standardized mortality ratio smr.

They included 60 88 2 female patients and 8 11 8 males. Sle accounts for 14 5 of all deaths from arthritis cdc unpublished data 1997 and represents one of these conditions that has premature mortality. Systemic lupus erythematosus sle is the most common type of lupus. The 5 yr survival rate for the total cohort was 96 2 95 confidence interval ci 93 4 99 0 and the total 10 yr survival rate was 87 4 95 ci 81 8 93 0.