Systemic Lupus Erythematosus Pathophysiology

Systemic lupus erythematosus may also occur in the form of periarticular inflammation that affects the tendon sheaths the illness causes the patient to experience coexisting fibromyalgia that results to poor sleep chronic disease inactivity mood problems and depression knott 2012. Continued types of lupus. Sle is an autoimmune disease in which the immune system attacks its own tissues causing widespread inflammation and tissue damage in the affected organs.

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Pathophysiology is defined as the study the biological and physical manifestations of disease as the correlate with the underlying abnormalities and physiological disturbances.

Systemic lupus erythematosus pathophysiology. Systemic lupus erythematosus sle is a chronic inflammatory disease that has protean manifestations and follows a relapsing and remitting course. In order to diagnose the disease at least 4 of the following 11 criteria must be met. Systemic lupus erythematosus sle cutaneous lupus which causes skin rashes or lesions drug induced lupus caused by a medication neonatal. Systemic lupus erythematosus sle is an autoimmune disease in which the body s immune system attacks its own healthy tissue.

It can affect the joints skin brain lungs kidneys and blood vessels. The main types of lupus are. Systemic lupus erythematosus sle is the most common type of lupus. Rash over the cheeks malar rash red raised patches discoid rash photosensitivity oral ulcers an inflammation of the joints that does not cause deformity an inflammation of membranes surrounding the lung or.

Severe fatigue joint pain joint swelling headaches a rash on the cheeks and nose which is called a butterfly rash hair loss anemia blood clotting problems fingers turning white or blue and tingling when cold which is known as raynaud s phenomenon. The patho aetiology of systemic lupus erythematosus sle probably involves complicated and multifactorial interactions among various genetic and environmental factors multiple genes contribute to disease susceptibility including genes encoding complement and other components of the immune response in addition to major histocompatibility complex class i and ii genes. More than 90 of cases of sle occur in women frequently starting at childbearing age.