Systemic Lupus Erythematosus Sle Diagnosis

Your doctor will do a physical exam to check for typical signs and symptoms of lupus including.

Systemic lupus erythematosus sle diagnosis. Sun sensitivity rashes such as a malar or butterfly rash mucous membrane ulcers which may occur in the mouth or nose arthritis which is swelling or tenderness of the small joints of the hands feet. Under normal circumstances the body s immune system produces antibodies against invading disease antigens to protect itself. Sle is an autoimmune disease in which the immune system attacks its own tissues causing widespread inflammation and tissue damage in the affected organs. The following are 11 criteria used for diagnosing systemic lupus erythematosus.

Systemic lupus erythematosus sle is a chronic autoimmune disease that causes a systemic inflammatory response in various parts of the body. The cause of sle is unknown but genetics and hormonal and environmental factors are involved. Malar rash over the cheeks of the face discoid skin rash patchy redness with hyperpigmentation and hypopigmentation that can cause scarring photosensitivity skin rash in reaction to sunlight ultraviolet light. Symptoms vary between people and may be mild to severe.

Before the diagnosis can be established four of 11 clinical and laboratory criteria must be. The diagnosis of sle is based on characteristic clinical findings of the skin joints kidneys and the central nervous system as well as on serological parameters such as antinuclear antibodies ana in particular antibodies to dsdna e1. Lupus technically known as systemic lupus erythematosus sle is an autoimmune disease in which the body s immune system mistakenly attacks healthy tissue in many parts of the body.